Most common medication for osteoporosis drugs containing Bisphosphonates ( a class of drug that is used for prevention of bone mass). Commonly, these drugs are used for osteoporosis treatment like Alendronate, Ibandronate, Risedronate, and Zoledronic acid. The side effects related to this kind of medication is rare and happens with people taking very high doses. Side effects include nausea, acid reflux and stomach pains.